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1 References  














Sulfoxone






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Sulfoxone
Skeletal formula of aldesulfone sodium
Space-filling model of the component ions of aldesulfone sodium
Clinical data
Routes of
administration
Oral
ATC code
Pharmacokinetic data
Protein binding69%
MetabolismHepatic
Elimination half-life3 to 8 hours
Identifiers
  • [4-[4-(sulfinomethylamino) phenyl] sulfonylphenyl] aminomethanesulfinic acid

CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H16N2Na2O6S3
Molar mass450.45 g·mol−1
3D model (JSmol)
  • [Na+].[Na+].[O-]S(=O)CNc1ccc(cc1)S(=O)(=O)c2ccc(NCS([O-])=O)cc2

  • InChI=1S/C14H16N2O6S3.2Na/c17-23(18)9-15-11-1-5-13(6-2-11)25(21,22)14-7-3-12(4-8-14)16-10-24(19)20;;/h1-8,15-16H,9-10H2,(H,17,18)(H,19,20);;/q;2*+1/p-2 checkY

  • Key:AZBNFLZFSZDPQF-UHFFFAOYSA-L checkY

 ☒NcheckY (what is this?)  (verify)

Sulfoxoneoraldesulfone sodium is an anti-leprosy drug.[1] It is also known as diasone. Sulfoxone sodium was introduced in Japan in 1948.[2] Ernest Muir introduced it to Western use while serving as superintendent of the Chacachacare LeprosariumonTrinidad in the Caribbean.[3]

References[edit]

  1. ^ "Sulfoxone".
  • ^ Ozawa H, Maruyama Y (2002). "[A 50-year history of new drugs in Japan: the developments of antileprosy drugs and their epidemiological aspects]". Yakushigaku Zasshi. 37 (1): 76–83. PMID 12412600.
  • ^ Browne, Stanley George (1974), "Ernest Muir, C.M.G., C.I.E., M.D. (Edin.), F.R.C.S., LL.D. 1880–1974" (PDF), International Journal of Leprosy, vol. 42, no. 4, Bauru: International Leprosy Association, pp. 457–458, PMID 4617724.

  • Retrieved from "https://en.wikipedia.org/w/index.php?title=Sulfoxone&oldid=1172421833"

    Categories: 
    Anilines
    Sulfonamides
    Antileprotic drugs
    Sulfonamide antibiotics
    Organic sodium salts
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    This page was last edited on 27 August 2023, at 00:07 (UTC).

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