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Names | |
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IUPAC name
4-Methoxy-6-(2-phenylethyl)-5,6-dihydro-2H-pyran-2-one | |
Other names
Dihydrokawain | |
Identifiers | |
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3D model (JSmol) |
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ChemSpider |
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PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C14H16O3 | |
Molar mass | 232.27 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
Dihydrokavain is one of the six major kavalactones found in the kava plant.[1] It appears to contribute significantly to the anxiolytic effects of kava, based on a study in chicks.[2]
Dihydrokavain bears some structural similarity to the strobilurins and has some fungicidal activity.[3]
An analogue of the molecule was also shown to improve glycemic control by modulating AMPK target genes expression in fruit flies.[4]
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History |
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Chemical composition |
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Alcohols |
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Barbiturates |
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Benzodiazepines |
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Carbamates |
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Flavonoids |
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Imidazoles |
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Kava constituents |
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Monoureides |
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Neuroactive steroids |
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Nonbenzodiazepines |
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Phenols |
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Piperidinediones |
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Pyrazolopyridines |
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Quinazolinones |
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Volatiles/gases |
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Others/unsorted |
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See also: Receptor/signaling modulators • GABA receptor modulators • GABA metabolism/transport modulators |
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