| |
| Names | |
|---|---|
| Preferred IUPAC name
O-[2-(Diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl phosphorothioate | |
| Other names
Pirimifos-methyl | |
| Identifiers | |
3D model (JSmol) |
|
| 755726 | |
| ChEBI | |
| ChemSpider |
|
| ECHA InfoCard | 100.045.011 
|
| EC Number |
|
| KEGG |
|
PubChem CID |
|
| UNII | |
| UN number | 3082 2902 |
CompTox Dashboard (EPA) |
|
| |
| |
| Properties | |
| C11H20N3O3PS | |
| Molar mass | 305.33 g·mol−1 |
| Appearance | Straw-colored liquid |
| Density | 1.147 g/mL (30 °C) |
| Melting point | 15 to 18 °C (59 to 64 °F; 288 to 291 K) |
| Boiling point | decomposes before boiling |
| 5.0 mg/L (30 °C) | |
| Hazards | |
| GHS labelling: | |
 
| |
| Warning | |
| H302, H410 | |
| P264, P270, P273, P301+P312, P330, P391, P501 | |
| Flash point | 46 °C (115 °F; 319 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
| |
Pirimiphos-methyl, marketed as Actellic[1][2][3][4] and Sybol, is a phosphorothioate used as an insecticide. It was originally developed by Imperial Chemical Industries Ltd., now Syngenta, at their Jealott's Hill site and first marketed in 1977, ten years after its discovery.[5][6]
This is one of several compounds used for vector control of Triatoma. These insects are implicated in the transmission of Chagas disease in the Americas.[7] Pirimiphos-methyl can be applied as an interior surface paint additive, in order to achieve a residual pesticide effect.
Pirimiphos methyl is manufactured in a two-step process in which N,N-diethylguanidine is reacted with ethyl acetoacetate to form a pyrimidine ring and its hydroxy group is combined with dimethyl chlorothiophosphate to form the insecticide.[8]
Pyrimiphos-ethyl is a related insecticide in which the methoxy groups are replaced with ethoxy groups.
