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| Names | |
|---|---|
| Preferred IUPAC name
4-(Dimethylamino)-3-methylphenyl methylcarbamate | |
| Other names
4-Dimethylamino-3-methylphenyl, N-Methylcarbamate | |
| Identifiers | |
3D model (JSmol) |
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| 2808681 | |
| ChEBI | |
| ChemSpider | |
| ECHA InfoCard | 100.016.356 
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| EC Number |
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PubChem CID |
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| RTECS number |
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| UNII | |
| UN number | 2811 |
CompTox Dashboard (EPA) |
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| Properties | |
| C11H16N2O2 | |
| Molar mass | 208.261 g·mol−1 |
| Appearance | White crystalline solid or tan crystals |
| Melting point | 95.0 °C (203.0 °F; 368.1 K) |
| Boiling point | 298 °C (568 °F; 571 K) |
| Soluble | |
| Solubility in other solvents | Soluble in polar org solvents; moderately soluble in aromatic solvents |
| Vapor pressure | 1.88 X 10-6 mm Hg |
Henry's law |
5.64 X 10-10 atm cu m/mole |
| Hazards | |
| Occupational safety and health (OHS/OSH): | |
Main hazards |
Maybe highly toxic by ingestion, toxic by skin absorption |
| GHS labelling: | |
 
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| Danger | |
| H301, H311, H400, H411[1] | |
| P264, P273, P280, P301+P310, P312 | |
| NFPA 704 (fire diamond) | |
| Flash point | 181 °C (358 °F; 454 K) |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose) |
Oral-rat-30 mg/kg and Dermal-rat-275 mg/kg |
| Safety data sheet (SDS) | [1] |
| Related compounds | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Animocarb (Matacil) is an organic chemical compound with the molecular formula C11H16N2O2. It has a colorless or white crystal-like appearance and is most commonly used as an insecticide.[2]
Aminocarb has been extensively used in eastern Canada since 1976 in order to control the spruce budworm. The fate of this chemical in the ecosystem and detection of aminocarb was studied by the use of two-dimensional thin-layer chromatography. The use of thin-layer chromatography helped isolate and identify the methyl amino, amino and hydroxymethyl analogues from the in vitro metabolism of aminocarb by liver homogenates from humans and rats.[3]
Aminocarb is a carbamate insecticide widely used to protect cotton fields, crop fields, and forests from insect infestation. It helps in the control of aphids, soil mollusks, lepidopterous larvae, and other types of chewing insects. It is most commonly administered as an aerosol spray.[4][5]
Aminocarb can be degraded through irradiation and hydrolysis.
Aminocarb can be broken down by short-wave ultraviolet radiation.[7] Irradiation is often carried out by a high pressure xenon-mercury lamp.[8] Irradiating aminocarb in ethyl alcohol and cyclohexene solutions initially causes the oxidation of the dimethylamine moiety.[7][9] The process eventually leads to the formation of a 4-dimethylamino-3-methyl phenol product.[9]
Aminocarb undergoes hydrolysisto4-dimethylamino-3-methylphenol in 25 °C purified water when pH of the water is 6.4. 4-dimethylamino-3-methylphenol is then either directly or via 2-methyl-1,4-dihydorquinone converted to 2-methyl-1,4-benzoquinone. If methylamineordiethylamine are present in the solution 2-methyl-1,4-benzoquinone will readily react. Monoepoxides and diepoxides of 2-methyl-1,4-benzoquinone are formed.[6]
In an experiment where young brown bullhead were exposed to aminocarb at lethal and sublethal concentrations, their tissue distribution was examined and showed that the concentration of residues in each tissue increased with the concentration of exposure of aminocarb. The liver and stomach/intestine had the highest amount of accumulation of residues.[10]
Aminocarb is also known as a cholinesterase inhibitor that has nervous system effects causing convulsions and respiratory failure. It can also be absorbed through the skin, causing long-term effects to the nervous system and liver.[11]
