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Contents

   



(Top)
 


1 References  





2 Further reading  





3 External links  














SIGLEC5






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SIGLEC5
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesSIGLEC5, CD170, CD33L2, OB-BP2, OBBP2, SIGLEC-5, sialic acid binding Ig like lectin 5
External IDsOMIM: 604200; HomoloGene: 55783; GeneCards: SIGLEC5; OMA:SIGLEC5 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003830
NM_001384708
NM_001384709

n/a

RefSeq (protein)

NP_003821

n/a

Location (UCSC)Chr 19: 51.61 – 51.63 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Sialic acid-binding Ig-like lectin 5 is a protein that in humans is encoded by the SIGLEC5 gene.[3][4] SIGLEC5 has also been designated CD170 (cluster of differentiation 170).


References[edit]

  • ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  • ^ Kim HS (Jun 1999). "Assignment of the human OB binding protein-2 gene (CD33L2) to chromosome 19q13.3 by radiation hybrid mapping". Cytogenet Cell Genet. 84 (1–2): 96. doi:10.1159/000015227. PMID 10343116. S2CID 10581090.
  • ^ "Entrez Gene: SIGLEC5 sialic acid binding Ig-like lectin 5".
  • Further reading[edit]

    • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Cornish AL, Freeman S, Forbes G, et al. (1998). "Characterization of siglec-5, a novel glycoprotein expressed on myeloid cells related to CD33". Blood. 92 (6): 2123–32. doi:10.1182/blood.V92.6.2123. PMID 9731071.
  • Patel N, Brinkman-Van der Linden EC, Altmann SW, et al. (1999). "OB-BP1/Siglec-6. A leptin- and sialic acid-binding protein of the immunoglobulin superfamily". J. Biol. Chem. 274 (32): 22729–38. doi:10.1074/jbc.274.32.22729. PMID 10428856.
  • Yousef GM, Ordon MH, Foussias G, Diamandis EP (2002). "Genomic organization of the siglec gene locus on chromosome 19q13.4 and cloning of two new siglec pseudogenes". Gene. 286 (2): 259–70. doi:10.1016/S0378-1119(02)00432-8. PMID 11943481.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Erickson-Miller CL, Freeman SD, Hopson CB, et al. (2003). "Characterization of Siglec-5 (CD170) expression and functional activity of anti-Siglec-5 antibodies on human phagocytes". Exp. Hematol. 31 (5): 382–8. doi:10.1016/S0301-472X(03)00046-8. PMID 12763136.
  • Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19". Nature. 428 (6982): 529–35. Bibcode:2004Natur.428..529G. doi:10.1038/nature02399. PMID 15057824.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Avril T, Freeman SD, Attrill H, et al. (2005). "Siglec-5 (CD170) can mediate inhibitory signaling in the absence of immunoreceptor tyrosine-based inhibitory motif phosphorylation" (PDF). J. Biol. Chem. 280 (20): 19843–51. doi:10.1074/jbc.M502041200. PMID 15769739. S2CID 44764751.
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
  • Rapoport EM, Pazynina GV, Sablina MA, et al. (2006). "Probing sialic acid binding Ig-like lectins (siglecs) with sulfated oligosaccharides". Biochemistry Mosc. 71 (5): 496–504. doi:10.1134/S0006297906050051. PMID 16732727. S2CID 11537303.
  • Biedermann B, Gil D, Bowen DT, Crocker PR (2007). "Analysis of the CD33-related siglec family reveals that Siglec-9 is an endocytic receptor expressed on subsets of acute myeloid leukemia cells and absent from normal hematopoietic progenitors". Leuk. Res. 31 (2): 211–20. doi:10.1016/j.leukres.2006.05.026. PMID 16828866.
  • Angata T, Hayakawa T, Yamanaka M, et al. (2006). "Discovery of Siglec-14, a novel sialic acid receptor undergoing concerted evolution with Siglec-5 in primates". FASEB J. 20 (12): 1964–73. doi:10.1096/fj.06-5800com. PMID 17012248. S2CID 13740587.
  • Zhuravleva MA, Trandem K, Sun PD (2007). "Structural Implications of Siglec-5-Mediated Sialoglycan Recognition". J. Mol. Biol. 375 (2): 437–47. doi:10.1016/j.jmb.2007.10.009. PMC 2245879. PMID 18022638.
  • External links[edit]



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    This page was last edited on 27 March 2024, at 22:53 (UTC).

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