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Contents

   



(Top)
  


1 References  




2 Further reading  




3 External links  













ZNF22






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From Wikipedia, the free encyclopedia
  

ZNF22

Identifiers

Aliases

ZNF22, HKR-T1, KOX15, ZNF422, Zfp422, zinc finger protein 22

External IDs

OMIM: 194529; MGI: 1914505; HomoloGene: 5067; GeneCards: ZNF22; OMA:ZNF22 - orthologs

Gene location (Human)

Chromosome 10 (human)

Chr.

Chromosome 10 (human)[1]

Chromosome 10 (human)

Genomic location for ZNF22

Genomic location for ZNF22

Band

10q11.21

Start

45,000,923 bp[1]

End

45,005,326 bp[1]

Gene location (Mouse)

Chromosome 6 (mouse)

Chr.

Chromosome 6 (mouse)[2]

Chromosome 6 (mouse)

Genomic location for ZNF22

Genomic location for ZNF22

Band

6|6 E3

Start

116,600,977 bp[2]

End

116,605,960 bp[2]

Bgee

Mouse (ortholog)

  • ventricular zone

  • ganglionic eminence

  • secondary oocyte

  • islet of Langerhans

  • body of pancreas

  • endometrium

  • lymph node

  • Achilles tendon

  • trabecular bone

  • tibia
    • ventricular zone

  • ganglionic eminence

  • genital tubercle

  • tail of embryo

  • neural tube

  • mesencephalon

  • thymus

  • epiblast

  • serous sac

  • stomach

    • More reference expression data

    BioGPS



    More reference expression data

    Molecular function

  • metal ion binding
  • DNA binding
  • nucleic acid binding
  • DNA-binding transcription factor activity, RNA polymerase II-specific

    • Cellular component

  • nucleoplasm

    • Biological process

  • regulation of transcription, DNA-templated
  • transcription, DNA-templated
  • regulation of transcription by RNA polymerase II

    • Sources:Amigo / QuickGO

    Species

    Human

    Mouse

    Entrez

    7570

    67255

    Ensembl

    ENSG00000165512

    ENSMUSG00000059878

    UniProt

    P17026

    Q9ERU3

    RefSeq (mRNA)

    NM_006963

    NM_026057
    NM_001302439
    NM_001302440

    RefSeq (protein)

    NP_008894
    NP_008894.2

    NP_001289368
    NP_001289369
    NP_080333

    Location (UCSC)

    Chr 10: 45 – 45.01 Mb

    Chr 6: 116.6 – 116.61 Mb

    PubMed search

    [3]

    [4]

    Wikidata

    Zinc finger protein 22 is a protein that in humans is encoded by the ZNF22 gene.[5]


    References[edit]

    1. ^ a b c GRCh38: Ensembl release 89: ENSG00000165512 – Ensembl, May 2017
  • ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000059878 – Ensembl, May 2017
  • ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  • ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  • ^ "Entrez Gene: ZNF22 zinc finger protein 22 (KOX 15)".

    • Further reading[edit]

  • Lichter P, Bray P, Ried T, et al. (1992). "Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes". Genomics. 13 (4): 999–1007. doi:10.1016/0888-7543(92)90013-I. PMID 1505991.
  • Rousseau-Merck MF, Tunnacliffe A, Berger R, et al. (1992). "A cluster of expressed zinc finger protein genes in the pericentromeric region of human chromosome 10". Genomics. 13 (3): 845–8. doi:10.1016/0888-7543(92)90166-P. PMID 1639412.
  • Bray P, Lichter P, Thiesen HJ, et al. (1991). "Characterization and mapping of human genes encoding zinc finger proteins". Proc. Natl. Acad. Sci. U.S.A. 88 (21): 9563–7. Bibcode:1991PNAS...88.9563B. doi:10.1073/pnas.88.21.9563. PMC 52758. PMID 1946370.
  • Huebner K, Druck T, Croce CM, Thiesen HJ (1991). "Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering". Am. J. Hum. Genet. 48 (4): 726–40. PMC 1682948. PMID 2014798.
  • Thiesen HJ (1991). "Multiple genes encoding zinc finger domains are expressed in human T cells". New Biol. 2 (4): 363–74. PMID 2288909.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Gao Y, Kobayashi H, Ganss B (2004). "The human KROX-26/ZNF22 gene is expressed at sites of tooth formation and maps to the locus for permanent tooth agenesis (He-Zhao deficiency)". J. Dent. Res. 82 (12): 1002–7. doi:10.1177/154405910308201213. PMID 14630903. S2CID 22367131.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

    • External links[edit]

    (1) Basic domains

    (1.1) Basic leucine zipper (bZIP)

  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 7
  • AP-1
  • BACH
  • BATF
  • BLZF1
  • C/EBP
  • CREB
  • CREM
  • DBP
  • DDIT3
  • GABPA
  • GCN4
  • HLF
  • MAF
  • NFE
  • NFIL3
  • NRL
  • NRF
  • XBP1

    • (1.2) Basic helix-loop-helix (bHLH)

    Group A

  • ASCL2
  • ATOH1
  • HAND
  • MESP2
  • Myogenic regulatory factors
  • NeuroD
  • Neurogenins
  • OLIG
  • Paraxis
  • SLC
  • Twist

    • Group B

  • Myc
  • MXD4
  • TCF4

    • Group C
    bHLH-PAS

  • AHRR
  • ARNT
  • CLOCK
  • HIF
  • NPAS
  • PER
  • SIM

    • Group D

    • BHLH
  • 3
  • 9
  • Pho4
  • ID

    • Group E

    • HES
  • 2
  • 3
  • 4
  • 5
  • 6
  • 7
  • HEY

    • Group F
    bHLH-COE

    (1.3) bHLH-ZIP

  • MAX
  • MITF
  • MNT
  • MLX
  • MLXIPL
  • MXI1
  • Myc
  • SREBP
  • USF1

    • (1.4) NF-1

  • B
  • C
  • X
  • SMAD

    • (1.5) RF-X

    • RFX
  • 2
  • 3
  • 4
  • 5
  • 6
  • ANK

    • (1.6) Basic helix-span-helix (bHSH)

  • β
  • γ
  • δ
  • ε

    • (2) Zinc finger DNA-binding domains

    (2.1) Nuclear receptor (Cys4)

    subfamily 1

  • β
  • CAR
  • FXR
  • LXR
  • PPAR
  • PXR
  • RAR
  • ROR
  • Rev-ErbA
  • VDR

    • subfamily 2

  • II
  • Ear-2
  • HNF4
  • PNR
  • RXR
  • Testicular receptor
  • TLX

    • subfamily 3

  • Estrogen
  • Glucocorticoid
  • Mineralocorticoid
  • Progesterone
  • Estrogen related

    • subfamily 4

  • NOR1
  • NURR1

    • subfamily 5

  • SF1

    • subfamily 6

    subfamily 0

  • SHP

    • (2.2) Other Cys4

  • 2
  • 3
  • 4
  • 5
  • 6
  • MTA
  • TRPS1

    • (2.3) Cys2His2

  • TFIIB
  • TFIID
  • TFIIE
  • TFIIF
  • 1
  • 2

    • (2.4) Cys6

    (2.5) Alternating composition

  • DIDO1
  • GRLF1
  • ING
  • JARID
  • JMJD1B

    • (2.6) WRKY

    (3) Helix-turn-helix domains

    Antennapedia
    ANTP class

    protoHOX
    Hox-like

  • 2
  • Xlox
  • Cdx
  • 2
  • 4
  • extended Hox: Evx1
  • Evx2
  • MEOX1
  • MEOX2
  • Homeobox
  • GBX1
  • GBX2
  • MNX1

    • metaHOX
    NK-like

  • BARHL2
  • BARX1
  • BARX2
  • BSX
  • DBX
  • DLX
  • EMX
  • EN
  • HHEX
  • HLX
  • LBX1
  • LBX2
  • MSX
  • NANOG
  • NKX
  • NATO
  • TLX1
  • TLX2
  • TLX3
  • VAX1
  • VAX2

    • other

  • CRX
  • CUTL1
  • FHL
  • HESX1
  • HOPX
  • LMX
  • NOBOX
  • TALE
  • PHF
  • POU domain
  • SATB2
  • ZEB

    • (3.2) Paired box

  • 2
  • 3
  • 4
  • 5
  • 6
  • 7
  • 8
  • 9
  • PRRX
  • PROP1
  • PHOX
  • RAX
  • SHOX
  • SHOX2
  • VSX1
  • VSX2
  • Bicoid

    • (3.3) Fork head / winged helix

  • 2
  • 3
  • 4
  • 5
  • FOX proteins

    • (3.4) Heat shock factors

  • 2
  • 4

    • (3.5) Tryptophan clusters

    • ELF
  • 4
  • 5
  • EGF
  • ELK
  • ERF
  • ETS
  • ETV
  • FLI1
  • Interferon regulatory factors
  • MYB
  • MYBL2

    • (3.6) TEA domain

    • transcriptional enhancer factor
  • 2
  • 3
  • 4

    • (4) β-Scaffold factors with minor groove contacts

  • NFKB2
  • REL
  • RELA
  • RELB
  • NFAT

    • (4.2) STAT

  • 2
  • 3
  • 4
  • 5
  • 6

    • (4.3) p53-like

  • TP63
  • p73
  • TBX
  • MYRF

    • (4.4) MADS box

  • B
  • C
  • D
  • SRF

    • (4.6) TATA-binding proteins

  • TBPL1

    • (4.7) High-mobility group

  • HMGB
  • HMGN
  • HNF
  • SOX
  • SRY
  • SSRP1
  • TCF/LEF
  • TOX

    • (4.9) Grainyhead

    (4.10) Cold-shock domain

  • YBX1

    • (4.11) Runt

  • CBFA2T3
  • RUNX1
  • RUNX2
  • RUNX3
  • RUNX1T1

    • (0) Other transcription factors

    (0.2) HMGI(Y)

  • 2
  • HBP1

    • (0.3) Pocket domain

  • RBL1
  • RBL2

    • (0.5) AP-2/EREBP-related factors

  • EREBP
  • B3

    • (0.6) Miscellaneous

  • 1B
  • 2
  • 3A
  • 3B
  • 4A
  • CAP
  • IFI
  • MLL
  • MNDA
  • NFY
  • Rho/Sigma

    • see also transcription factor/coregulator deficiencies


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    • Retrieved from "https://en.wikipedia.org/w/index.php?title=ZNF22&oldid=1116626322"
    Categories: 
    ●Genes on human chromosome 10
     ●Transcription factors
     ●Protein stubs
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    ●This page was last edited on 17 October 2022, at 14:36 (UTC).
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