Contents

60S ribosomal protein L13a

Protein found in humans

RPL13A
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4UG0, 4V6X, 5AJ0, 4UJD, 4D67, 4D5Y, 4UJE, 4UJC
Identifiers
Aliases	RPL13A, L13A, TSTA1, ribosomal protein L13a
External IDs	MGI: 1351455; HomoloGene: 111053; GeneCards: RPL13A; OMA:RPL13A - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19q13.33 Start 49,487,510 bp[1] End 49,493,057 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7 B3|7 29.14 cM Start 44,774,982 bp[2] End 44,778,185 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left ovary right ovary right uterine tube canal of the cervix skin of abdomen ganglionic eminence skin of leg ectocervix right lobe of thyroid gland body of uterus Top expressed in ventricular zone urinary bladder yolk sac ganglionic eminence lip ovary thymus adrenal gland neural layer of retina spleen More reference expression data BioGPS n/a
Gene ontology Molecular function mRNA binding RNA binding structural constituent of ribosome Cellular component cytoplasm cytosol ribosome membrane focal adhesion large ribosomal subunit nucleolus GAIT complex cytosolic large ribosomal subunit nucleus ribonucleoprotein complex Biological process negative regulation of translation viral transcription SRP-dependent cotranslational protein targeting to membrane negative regulation of formation of translation preinitiation complex cellular response to interferon-gamma translational initiation nuclear-transcribed mRNA catabolic process, nonsense-mediated decay regulation of translation protein biosynthesis rRNA processing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23521 22121 Ensembl ENSG00000142541 ENSMUSG00000074129 UniProt P40429 P19253 RefSeq (mRNA) NM_001270491 NM_012423 NM_009438 RefSeq (protein) NP_001257420 NP_036555 NP_033464 Location (UCSC) Chr 19: 49.49 – 49.49 Mb Chr 7: 44.77 – 44.78 Mb PubMed search [3] [4]
Wikidata
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60S ribosomal protein L13a is a protein that in humans is encoded by the RPL13A gene.^[5]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L13P family of ribosomal proteins. It is located in the cytoplasm. Transcript variants utilizing alternative polyA signals have been observed. This gene is co-transcribed with the small nucleolar RNA genes U32, U33, U34, and U35, which are located in its second, fourth, fifth, and sixth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[5]

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