Importing Wikidata short description: "Protein-coding gene in the species Homo sapiens"
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[[Category:Keratins]] |
[[Category:Keratins]] |
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{{Gene-17-stub}} |
Keratin 14 is a member of the type I keratin family of intermediate filament proteins. Keratin 14 was the first type I keratin sequence determined.[5] Keratin 14 is also known as cytokeratin-14 (CK-14) or keratin-14 (KRT14). In humans it is encoded by the KRT14 gene.[6][7][8]
Keratin 14 is usually found as a heterodimer with type II keratin 5 and form the cytoskeletonofepithelial cells.
Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex[9] and dermatopathia pigmentosa reticularis, both of which are autosomal dominant mutations.[10]
Proteins of the cytoskeleton
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See also: cytoskeletal defects |
This article on a gene on human chromosome 17 is a stub. You can help Wikipedia by expanding it. |