Jump to content
 







Main menu
   


Navigation  



Main page
Contents
Current events
Random article
About Wikipedia
Contact us
Donate
 




Contribute  



Help
Learn to edit
Community portal
Recent changes
Upload file
 








Search  

































Create account

Log in
 









Create account
 Log in
 




Pages for logged out editors learn more  



Contributions
Talk
 



















Contents

   



(Top)
 


1 References  





2 External links  














EGF module-containing mucin-like hormone receptor






فارسی
Српски / srpski
Srpskohrvatski / српскохрватски

 

Edit links
 









Article
Talk
 

















Read
Edit
View history
 








Tools
   


Actions  



Read
Edit
View history
 




General  



What links here
Related changes
Upload file
Special pages
Permanent link
Page information
Cite this page
Get shortened URL
Download QR code
Wikidata item
 




Print/export  



Download as PDF
Printable version
 
















Appearance
   

 






From Wikipedia, the free encyclopedia
 


egf-like module containing, mucin-like, hormone receptor-like 1
Identifiers
SymbolEMR1
Alt. symbolsTM7LN3
IUPHAR182
NCBI gene2015
HGNC3336
OMIM600493
RefSeqNM_001974
UniProtQ14246
Other data
LocusChr. 19 p13.3
Search for
StructuresSwiss-model
DomainsInterPro
egf-like module containing, mucin-like, hormone receptor-like 2
Identifiers
SymbolEMR2
IUPHAR183
NCBI gene30817
HGNC3337
OMIM606100
RefSeqNM_152916
UniProtQ9UHX3
Other data
LocusChr. 19 p13.1
Search for
StructuresSwiss-model
DomainsInterPro
egf-like module containing, mucin-like, hormone receptor-like 3
Identifiers
SymbolEMR3
IUPHAR184
NCBI gene84658
HGNC23647
OMIM606101
RefSeqNM_032571
UniProtQ9BY15
Other data
LocusChr. 19 p13.1
Search for
StructuresSwiss-model
DomainsInterPro
egf-like module containing, mucin-like, hormone receptor-like 4 pseudogene
Identifiers
SymbolEMR4P
Alt. symbolsGPR127
NCBI gene326342
HGNC19240
RefSeqXM_940358
UniProtQ86SQ3
Other data
LocusChr. 19 p13.3
Search for
StructuresSwiss-model
DomainsInterPro

The EGF module-containing Mucin-like hormone Receptors (EMRs) are closely related subgroup of G protein-coupled receptors (GPCRs). These receptors have a unique hybrid structure in which an extracellular epidermal growth factor (EGF)-like domain is fused to a GPCR domain through a mucin-like stalk.[1][2][3][4] There are four variants of EMR labeled 1–4, each encoded by a separate gene. These receptors are predominantly expressed in cells of the immune system and bind ligands such as CD55.[5]

References[edit]

  1. ^ Baud V, Chissoe SL, Viegas-Péquignot E, Diriong S, N'Guyen VC, Roe BA, Lipinski M (1995). "EMR1, an unusual member in the family of hormone receptors with seven transmembrane segments". Genomics. 26 (2): 334–44. doi:10.1016/0888-7543(95)80218-B. PMID 7601460.
  • ^ Lin HH, Stacey M, Hamann J, Gordon S, McKnight AJ (2000). "Human EMR2, a novel EGF-TM7 molecule on chromosome 19p13.1, is closely related to CD97". Genomics. 67 (2): 188–200. doi:10.1006/geno.2000.6238. PMID 10903844.
  • ^ Stacey M, Lin HH, Hilyard KL, Gordon S, McKnight AJ (2001). "Human epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 is a new member of the EGF-TM7 family that recognizes a ligand on human macrophages and activated neutrophils". J. Biol. Chem. 276 (22): 18863–70. doi:10.1074/jbc.M101147200. PMID 11279179.
  • ^ Caminschi I, Vandenabeele S, Sofi M, McKnight AJ, Ward N, Brodnicki TC, Toy T, Lahoud M, Maraskovsky E, Shortman K, Wright MD (2006). "Gene structure and transcript analysis of the human and mouse EGF-TM7 molecule, FIRE". DNA Seq. 17 (1): 8–14. doi:10.1080/10425170500355737. PMID 16753812. S2CID 11216477.
  • ^ Kwakkenbos MJ, Kop EN, Stacey M, Matmati M, Gordon S, Lin HH, Hamann J (2004). "The EGF-TM7 family: a postgenomic view". Immunogenetics. 55 (10): 655–66. doi:10.1007/s00251-003-0625-2. PMID 14647991. S2CID 28689160.
  • External links[edit]


  • t
  • e

  • Retrieved from "https://en.wikipedia.org/w/index.php?title=EGF_module-containing_mucin-like_hormone_receptor&oldid=1188166162"

    Categories: 
    Genes on human chromosome 19
    G protein-coupled receptors
    Transmembrane receptor stubs
    Hidden categories: 
    Articles with short description
    Short description is different from Wikidata
    Articles with topics of unclear notability from February 2021
    All articles with topics of unclear notability
    Protein pages needing a picture
    All stub articles
     



    This page was last edited on 3 December 2023, at 19:08 (UTC).

    Text is available under the Creative Commons Attribution-ShareAlike License 4.0; additional terms may apply. By using this site, you agree to the Terms of Use and Privacy Policy. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc., a non-profit organization.



    Privacy policy

    About Wikipedia

    Disclaimers

    Contact Wikipedia

    Code of Conduct

    Developers

    Statistics

    Cookie statement

    Mobile view



    Wikimedia Foundation
    Powered by MediaWiki