P2Y purinoceptor 8 is a protein that in humans is encoded by the P2RY8 gene.[3][4]
The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y.[4]
Recurrent mutations in this gene have been associated to cases of diffuse large B-cell lymphoma.[5]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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Receptor (ligands) |
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Transporter (blockers) |
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Enzyme (inhibitors) |
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Others |
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See also: Receptor/signaling modulators |
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