Contents

BACH2

Protein-coding gene in the species Homo sapiens

BACH2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3OHU, 3OHV
Identifiers
Aliases	BACH2, BTBD25, BTB domain and CNC homolog 2, IMD60
External IDs	OMIM: 605394; MGI: 894679; HomoloGene: 7240; GeneCards: BACH2; OMA:BACH2 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6q15 Start 89,926,528 bp[1] End 90,296,843 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 A5 Start 32,238,804 bp[2] End 32,586,108 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve epithelium of nasopharynx oocyte bone marrow secondary oocyte thymus ganglionic eminence tonsil lymph node ventricular zone Top expressed in zygote mesenteric lymph nodes trigeminal ganglion Rostral migratory stream blood tibiofemoral joint spleen hand hair follicle ganglionic eminence More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA-binding transcription factor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific ubiquitin-protein transferase activity DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component cytoplasm Cul3-RING ubiquitin ligase complex nucleus cytosol Biological process regulation of transcription, DNA-templated negative regulation of transcription by RNA polymerase II transcription by RNA polymerase II transcription, DNA-templated protein ubiquitination import into nucleus Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 60468 12014 Ensembl ENSG00000112182 ENSMUSG00000040270 UniProt Q9BYV9 P97303 RefSeq (mRNA) NM_001170794 NM_021813 NM_001109661 NM_007521 RefSeq (protein) NP_001164265 NP_068585 NP_001103131 Location (UCSC) Chr 6: 89.93 – 90.3 Mb Chr 4: 32.24 – 32.59 Mb PubMed search [3] [4]
Wikidata
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Transcription regulator protein BACH2 (broad complex-tramtrack-bric a brac and Cap'n'collar homology 2) is a protein that in humans is encoded by the BACH2 gene.^[5][6][7] It contains a BTB/POZ domain at its N-terminus which forms a disulphide-linked dimer ^[8] and a bZip_Maf domain at the C-terminus.

• BACH2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
• Human BACH2 genome location and BACH2 gene details page in the UCSC Genome Browser.
• Overview of all the structural information available in the PDB for UniProt: Q9BYV9 (Transcription regulator protein BACH2) at the PDBe-KB.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.