Fos-related antigen 2 (FRA2) is a protein that in humans is encoded by the FOSL2 gene.[5]
The Fos gene family consists of 4 members: c-Fos, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.[5]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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