Homeobox protein Hox-B9 is a protein that in humans is encoded by the HOXB9 gene.[5][6][7]
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer.[7]
HOXB9 has been shown to interact with BTG2[8] and BTG1.[8]
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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