The trade with Arabia and India in incense and spices became increasingly important, and Greeks for the first time began to trade directly with India. The discovery, or rediscovery, of the sea-route to India is attributed to a certain Eudoxos, who was sent out for this purpose towards the end of the reign of Ptolemy Euergetes II (died 116 BC). Eudoxos made two voyages to India, and subsequently, having quarrelled with his Ptolemaic employers, perished in an unsuccessful attempt to open up an alternative sea route to India, free of Ptolemaic control, by sailing around Africa. The establishment of direct contacts between Egypt and India was probably made possible by a weakening of Arab power at this period, for the Sabaean kingdom of South-western Arabia collapsed and was replaced by Himyarite Kingdom around 115 BC. Imports into Egypt of cinnamon and other eastern spices, such as pepper, increased substantially, though the Indian Ocean trade remained for the moment on quite a small scale, no more than twenty Egyptian ships venturing outside the Red Sea each year.
In 1602 the Dutch East India Company came into existence by authority of the Estates-General of the Netherlands. In 1664 the French East India Company was organized by state authorization under Louis XIV. Other European nations granted charters to East India companies with varying success. There followed struggles and conquests to gain advantage and monopolistic control of the trade. For more than 100 years Portugal was the dominant power, eventually yielding to English and Dutch enterprise and conquest; by the 19th century British interests were firmly rooted in India and Ceylon, and the Dutch were in control over the greater part of the East Indies.
Trade by Europeans between different parts of South and East Asia was often more profitable than supplying the home countries. In the 1530s, the Portuguese shipped substantially more cloves, nutmegs, and mace to India and Hormuz than to Portugal. The buyers in Hormuz were "Moorish merchants who pass[ed] it on, over Persia, Arabia and all Asia as far as Turkey." From at least the seventeenth century, the same products were taken to Bengal by the Portuguese and the Dutch. English merchants found that they sold "Exceedingly well in Surratt" and other Indian and Persian stations. The Dutch between 1620 and 1740 marketed one-third or more of their spices, notably cloves, in Asia: Persia, Arabia, and India. Japan was served by the Portuguese from Macau and later by the Dutch, but the demand for cloves and spices generally was said in the early seventeenth century to be relatively small and prices were consequently low.
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